Tirzepatide for weight loss: how Mounjaro works
Medically reviewed by Dr Miguel A. Guirola
Obesity specialist doctor · DoctorLife doctor
GMC-registered · General Medical Council
Medically reviewed by Dr Miguel A. Guirola
Obesity specialist doctor · DoctorLife doctor
GMC-registered · General Medical Council
Tirzepatide is the active ingredient in Mounjaro and the most effective GLP-1 in trials. Here is how it works for weight loss.
Tirzepatide is a dual GIP/GLP-1 agonist, meaning it acts on two appetite-regulating pathways. In clinical trials it produced the greatest average weight loss of the current GLP-1 medicines (up to around 20%). It is sold in the UK as Mounjaro and is prescription-only.
People who started their plan with medical supervision. Swipe to see more cases.



Results achieved with GLP-1-based medical treatment. Illustrative images. Results depend on each individual and on the medical assessment; they are not guaranteed.
Yes. Tirzepatide is the active ingredient; Mounjaro is the brand name sold in the UK.
Average weight loss in trials was up to around 20%, but individual results depend on dose, adherence and lifestyle.
This content is informational and does not replace medical advice. GLP-1 treatments require assessment and a prescription from a GMC-registered clinician. Content reviewed by Dr Miguel A. Guirola (GMC-registered · General Medical Council).
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