Weight loss

Tirzepatide for weight loss: how Mounjaro works

Updated 16 June 20266 min read
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Medically reviewed by Dr Miguel A. Guirola

Obesity specialist doctor · DoctorLife doctor

GMC-registered · General Medical Council

We treat patients in the UK and the surrounding area — online medical consultations, no travel needed.

Tirzepatide is the active ingredient in Mounjaro and the most effective GLP-1 in trials. Here is how it works for weight loss.

How does tirzepatide work?

Tirzepatide is a dual GIP/GLP-1 agonist, meaning it acts on two appetite-regulating pathways. In clinical trials it produced the greatest average weight loss of the current GLP-1 medicines (up to around 20%). It is sold in the UK as Mounjaro and is prescription-only.

Real results with GLP-1 treatment

People who started their plan with medical supervision. Swipe to see more cases.

BeforeAfter
Before and after of a weight management case with GLP-1 treatment
−14 kgin 20 weeks
Before and after of a weight management case with GLP-1 treatment
−18 kgin 24 weeks
Before and after of a weight management case with GLP-1 treatment
−16 kgin 22 weeks

Results achieved with GLP-1-based medical treatment. Illustrative images. Results depend on each individual and on the medical assessment; they are not guaranteed.

Frequently asked questions

Is tirzepatide the same as Mounjaro?+

Yes. Tirzepatide is the active ingredient; Mounjaro is the brand name sold in the UK.

How much weight can I lose with tirzepatide?+

Average weight loss in trials was up to around 20%, but individual results depend on dose, adherence and lifestyle.

This content is informational and does not replace medical advice. GLP-1 treatments require assessment and a prescription from a GMC-registered clinician. Content reviewed by Dr Miguel A. Guirola (GMC-registered · General Medical Council).

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